So I’ve been booked in for my LEI procedure next Wednesday at 8am.
Has anyone had this procedure before and can provide some info on it?
This is what I’ve managed to dig up:
A healthy young woman has approximately a 25% chance to achieve a successful pregnancy with each menstrual cycle. After about 1 year of trying to become pregnant, 15% of couples will remain unsuccessful. At that point, an evaluation is typically done and some type of fertility treatment is initiated. If fertility treatments fail repeatedly, in vitro fertilization (IVF) is eventually recommended. This treatment offers the best per-attempt chance for pregnancy, which is why patients have the highest level of expectation for treatment success. Therefore, it is not surprising that unsuccessful IVF can lead to significant disappointment. When insurance does not cover the treatment, expenses can also be significant. This results in much pressure on both the patients and the treating team.
Despite these expectations, the overall live birth rate is only 30% with IVF. In most cases, this is a consequence of problems (mainly aneuploidy) with the embryo. Several other factors (eg, endometriosis, fibroids, adenomyosis, immunologic or hematologic problems, hydrosalpinx) can also reduce success rates. When treatments fail repeatedly, the evaluation can be extended and certain additional therapeutic measures can be offered.
The benefit of endometrial “injury” induced before the start of IVF treatment has been evaluated in recent years. Several mechanisms are believed to play a role in improving the outcome with this intervention. After endometrial injury, cytokines that are released during the repair process induce endometrial changes favorable for implantation. Endometrial injury also induces decidualization, which favors implantation as well. The healing after the injury slows endometrial development, which is otherwise accelerated after stimulation, thereby increasing the likelihood for an in-phase endometrium at the time of transfer. This review summarizes the available evidence about the effect of intentional endometrial injury on IVF success rates.